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[The polymorphism in intron 4 of endothelial nitric oxide synthase altered endothelial response to folate significantly: in subjects with diabetes FMD improved by 6.4 � 5% (insertion carriers) vs 2.3 � 6.6% (deletion carriers), P = .01; in obese subjects FMD improved by 1.8 � 5.4% (insertion carriers) and deteriorated by -3.2 � 7.2% (deletion carriers), P = .05.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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