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[Direct intratumoral injection of 100 microg of a IFN-omega pDNA DMRIE/DOPE complex (1:1 DNA:DMRIE mass ratio) for 6 consecutive days resulted in a significant reduction in the tumor volume of NIH: OVCAR-3 ovarian carcinoma or A375 melanoma (P = 0.02).IFN-omega pDNA delivered by i.m. injection also had an antitumor effect.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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